Integrins and p53 pathways in glioblastoma resistance to temozolomide

Glioblastoma is the most common malignant primary brain tumor. Surgical resection, postoperative radiotherapy plus concomitant and adjuvant chemotherapy with temozolomide is the standard of care for newly diagnosed glioblastoma. In the past decade, efforts have been made to decipher genomic and core...

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Bibliographic Details
Main Authors: Monique eDontenwill, Sophie eMartin, Hana eJanouskova
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Oncology
Subjects:
p53
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00157/full