Biomarker Supervised G-CSF (Filgrastim) Response in ALS Patients

Biomarker Supervised G-CSF (Filgrastim) Response in ALS Patients

Objective: To evaluate safety, tolerability and feasibility of long-term treatment with Granulocyte-colony stimulating factor (G-CSF), a well-known hematopoietic stem cell factor, guided by assessment of mobilized bone marrow derived stem cells and cytokines in the serum of patients with amyotrophic...

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Bibliographic Details
Main Authors: Siw Johannesen, Bettina Budeus, Sebastian Peters, Sabine Iberl, Anne-Louise Meyer, Tina Kammermaier, Eva Wirkert, Tim-Henrik Bruun, Verena C. Samara, Wilhelm Schulte-Mattler, Wolfgang Herr, Armin Schneider, Jochen Grassinger, Ulrich Bogdahn
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Neurology
Subjects:
amyotrophic lateral sclerosis
granulocyte-colony stimulating factor
cytokines
hematopoietic stem and progenitor cells
HSPC
treatment
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00971/full

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https://www.frontiersin.org/article/10.3389/fneur.2018.00971/full

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