The Novel Small-molecule Annexin-A1 Mimetic, Compound 17b, Elicits Vasoprotective Actions in Streptozotocin-induced Diabetic Mice

The Novel Small-molecule Annexin-A1 Mimetic, Compound 17b, Elicits Vasoprotective Actions in Streptozotocin-induced Diabetic Mice

The formyl peptide receptor (FPR) family are a group of G-protein coupled receptors that play an important role in the regulation of inflammatory processes. It is well-established that activation of FPRs can have cardioprotective properties. Recently, more stable small-molecule FPR1/2 agonists have...

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Bibliographic Details
Main Authors: Sarah A Marshall, Cheng Xue Qin, Maria Jelinic, Kelly O’Sullivan, Minh Deo, Jesse Walsh, Mandy Li, Laura J Parry, Rebecca H. Ritchie, Chen Huei Leo
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
diabetes
compound 17b
endothelial dysfunction
fpr1/2
Online Access:https://www.mdpi.com/1422-0067/21/4/1384

Internet

https://www.mdpi.com/1422-0067/21/4/1384

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