Beyond negative valence: 2-week administration of a serotonergic antidepressant enhances both reward and effort learning signals.

To make good decisions, humans need to learn about and integrate different sources of appetitive and aversive information. While serotonin has been linked to value-based decision-making, its role in learning is less clear, with acute manipulations often producing inconsistent results. Here, we show...

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Bibliographic Details
Main Authors: Jacqueline Scholl, Nils Kolling, Natalie Nelissen, Michael Browning, Matthew F S Rushworth, Catherine J Harmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-02-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2000756