CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS

CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS

Amyotrophic lateral sclerosis (ALS) is characterized by degeneration of upper and lower motor neurons accompanied by proliferation of reactive microglia in affected regions. However, it is unknown whether the hematopoietic marker CD34 can identify a subpopulation of proliferating microglial cells in...

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Bibliographic Details
Main Authors: Mariángeles Kovacs, Emiliano Trias, Valentina Varela, Sofia Ibarburu, Joseph S. Beckman, Ivan C. Moura, Olivier Hermine, Peter H. King, Ying Si, Yuri Kwon, Luis Barbeito
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:International Journal of Molecular Sciences
Subjects:
microglia
CD34
amyotrophic lateral sclerosis
misfolded SOD1
motor neurons
Online Access:https://www.mdpi.com/1422-0067/20/16/3880

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https://www.mdpi.com/1422-0067/20/16/3880

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