Deciphering the interleukin 28B variants that better predict response to pegylated interferon-α and ribavirin therapy in HCV/HIV-1 coinfected patients.

Deciphering the interleukin 28B variants that better predict response to pegylated interferon-α and ribavirin therapy in HCV/HIV-1 coinfected patients.

Previous works have documented the contribution of different IL28B-associated SNPs to spontaneous HCV clearance. This study investigated the effect of different interleukin (IL) 28B genetic variants on interferon (IFN)-based therapy response. We genotyped eight IL28B single-nucleotide polymorphisms...

Full description

Bibliographic Details
Main Authors: Montserrat de Castellarnau, Ester Aparicio, Mariona Parera, Sandra Franco, Cristina Tural, Bonaventura Clotet, Miguel Angel Martínez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3273458?pdf=render

Internet

http://europepmc.org/articles/PMC3273458?pdf=render

Similar Items