The promyelocytic leukemia zinc finger protein (PLZF): two decades of molecular oncology

The promyelocytic leukemia zinc finger protein (PLZF): two decades of molecular oncology

The promyelocytic leukemia zinc finger protein (PLZF), also known as Zbtb16 or Zfp145, was first identified in a patient with acute promyelocytic leukemia, where a reciprocal chromosomal translocation t(11;17)(q23;q21) resulted in a fusion with the RARA gene encoding retinoic acid receptor alpha. Th...

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Bibliographic Details
Main Authors: Bandar Ali Suliman, Dakang eXu, Bryan Raymond George Williams
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-07-01
Series:Frontiers in Oncology
Subjects:
Apoptosis
Cell Cycle
Cytokines
Leukemia
Cancer
stem cell
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00074/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00074/full

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