Within-population genetic diversity and population structure of Plasmodium knowlesi merozoite surface protein 1 gene from geographically distinct regions of Malaysia and Thailand

Within-population genetic diversity and population structure of Plasmodium knowlesi merozoite surface protein 1 gene from geographically distinct regions of Malaysia and Thailand

Abstract Background The C-terminal 42 kDa domain of Plasmodium knowlesi merozoite surface protein 1 (PkMSP1) is a potential asexual blood-stage vaccine candidate, however, only a limited number of clinical isolates have been analysed from Malaysia and no inter-country comparative diversity study has...

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Bibliographic Details
Main Authors: Md Atique Ahmed, Ki-Back Chu, Indra Vythilingam, Fu-Shi Quan
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Malaria Journal
Subjects:
Merozoite surface protein 1
Natural selection
Vaccine
Genetic diversity
Sub-populations
Plasmodium knowlesi
Online Access:http://link.springer.com/article/10.1186/s12936-018-2583-z

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http://link.springer.com/article/10.1186/s12936-018-2583-z

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