Prognostic Value of Germline Copy Number Variants and Environmental Exposures in Non-small Cell Lung Cancer

Prognostic Value of Germline Copy Number Variants and Environmental Exposures in Non-small Cell Lung Cancer

Germline copy number variant (gCNV) has been studied as a genetic determinant for prognosis of several types of cancer, but little is known about how it affects non-small cell lung cancer (NSCLC) prognosis. We aimed to develop a prognostic nomogram for NSCLC based on gCNVs. Promising gCNVs that are...

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Bibliographic Details
Main Authors: Shizhen Chen, Liming Lu, Jianfeng Xian, Changhong Shi, Jinbin Chen, Boqi Rao, Fuman Qiu, Jiachun Lu, Lei Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Genetics
Subjects:
germline copy number variant
non-small cell lung cancer
overall survival
gene-environment interaction
nomogram
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.681857/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.681857/full

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