Chromatin Landscape Distinguishes the Genomic Loci of Hundreds of Androgen-Receptor-Associated LincRNAs From the Loci of Non-associated LincRNAs

Chromatin Landscape Distinguishes the Genomic Loci of Hundreds of Androgen-Receptor-Associated LincRNAs From the Loci of Non-associated LincRNAs

Cell signaling events triggered by androgen hormone in prostate cells is dependent on activation of the androgen receptor (AR) transcription factor. Androgen hormone binding to AR promotes its displacement from the cytoplasm to the nucleus and AR binding to DNA motifs, thus inducing activatory and i...

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Bibliographic Details
Main Authors: Lucas F. daSilva, Felipe C. Beckedorff, Ana C. Ayupe, Murilo S. Amaral, Vinícius Mesel, Alexandre Videira, Eduardo M. Reis, João C. Setubal, Sergio Verjovski-Almeida
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Genetics
Subjects:
long intergenic non-coding RNAs
androgen receptor
androgen receptor associated lincRNAs
genome-wide profiling
epigenetic marks
LNCaP prostate cancer cell line
Online Access:http://journal.frontiersin.org/article/10.3389/fgene.2018.00132/full

Internet

http://journal.frontiersin.org/article/10.3389/fgene.2018.00132/full

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