Fronts and waves of actin polymerization in a bistability-based mechanism of circular dorsal ruffles

Circular dorsal ruffles (CDRs) are important for the vesicular uptake of extracellular matter, but the basis of their wave dynamics is not understood. Here, the authors propose and experimentally test a bistable reaction-diffusion system, which they show accounts for the typical CDR expansion and sh...

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Bibliographic Details
Main Authors: Erik Bernitt, Hans-Günther Döbereiner, Nir S. Gov, Arik Yochelis
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms15863