The Janus Face of NKT Cell Function in Autoimmunity and Infectious Diseases

The Janus Face of NKT Cell Function in Autoimmunity and Infectious Diseases

Natural killer T cells (NKT) are a subset of T lymphocytes bridging innate and adaptive immunity. These cells recognize self and microbial glycolipids bound to non-polymorphic and highly conserved CD1d molecules. Three NKT cell subsets, type I, II, and NKT-like expressing different antigen receptors...

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Bibliographic Details
Main Authors: Alessandra Torina, Giuliana Guggino, Marco Pio La Manna, Guido Sireci
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:International Journal of Molecular Sciences
Subjects:
microbes
autoimmunity
glycolipids
alpha-galactosylceramide
sulfatide
CD1d
NKT
Online Access:http://www.mdpi.com/1422-0067/19/2/440

Internet

http://www.mdpi.com/1422-0067/19/2/440

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