Lipopolysaccharide induces inflammatory hyperalgesia triggering a TLR4/MyD88-dependent cytokine cascade in the mice paw.

Lipopolysaccharide induces inflammatory hyperalgesia triggering a TLR4/MyD88-dependent cytokine cascade in the mice paw.

Inflammatory pain can be triggered by different stimuli, such as trauma, radiation, antigen and infection. In a model of inflammatory pain caused by infection, injection in the mice paw of lipopolysaccharide (LPS), a Toll-like receptor 4 (TLR4) agonist, produces mechanical hyperalgesia. We identify...

Full description

Bibliographic Details
Main Authors: Igor L Calil, Ana C Zarpelon, Ana T G Guerrero, Jose C Alves-Filho, Sergio H Ferreira, Fernando Q Cunha, Thiago M Cunha, Waldiceu A Verri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24595131/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24595131/?tool=EBI

Similar Items