Effects of metformin on inflammation, oxidative stress, and bone loss in a rat model of periodontitis.

Effects of metformin on inflammation, oxidative stress, and bone loss in a rat model of periodontitis.

To evaluate the effects of metformin (Met) on inflammation, oxidative stress, and bone loss in a rat model of ligature-induced periodontitis.Male albino Wistar rats were divided randomly into five groups of twenty-one rats each, and given the following treatments for 10 days: (1) no ligature + water...

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Bibliographic Details
Main Authors: Aurigena Antunes de Araújo, Aline de Sousa Barbosa Freitas Pereira, Caroline Addison Carvalho Xavier de Medeiros, Gerly Anne de Castro Brito, Renata Ferreira de Carvalho Leitão, Lorena de Souza Araújo, Paulo Marcos Matta Guedes, Sarah Hiyari, Flávia Q Pirih, Raimundo Fernandes de Araújo Júnior
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5573680?pdf=render

Internet

http://europepmc.org/articles/PMC5573680?pdf=render

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