Managing cardiovascular and renal risk: the potential of direct renin inhibition

Aliskiren is the first direct renin inhibitor for the treatment of hypertension. Clinical experience from studies in over 14,000 patients has shown that aliskiren, alone or in combination with other antihypertensive therapies, provides effective blood pressure lowering with a good safety and tolerab...

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Bibliographic Details
Main Authors: Peter S Sever, Alan H Gradman, Michel Azizi
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2009-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320309104662