CircRILPL1 promotes muscle proliferation and differentiation via binding miR-145 to activate IGF1R/PI3K/AKT pathway

Abstract Many novel non-coding RNAs, such as microRNAs (miRNAs) and circular RNAs (circRNAs), are involved in various physiological and pathological processes. The PI3K/AKT signaling pathway is important for its role in regulating skeletal muscle development. In this study, molecular and biochemical...

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Bibliographic Details
Main Authors: Xuemei Shen, Jia Tang, Rui Jiang, Xiaogang Wang, Zhaoxin Yang, Yongzhen Huang, Xianyong Lan, Chuzhao Lei, Hong Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03419-y