Adolescent frontal top-down neurons receive heightened local drive to establish adult attentional behavior in mice

Frontal top-down cortical neurons implement top-down attentional control of sensory regions. The authors reveal adolescence as a developmental stage when frontal top-down neurons projecting from the anterior cingulate to visual cortex are functionally integrated into local excitatory circuitry.

Bibliographic Details
Main Authors: Elisa M. Nabel, Yury Garkun, Hiroyuki Koike, Masato Sadahiro, Ana Liang, Kevin J. Norman, Giulia Taccheri, Michael P. Demars, Susanna Im, Keaven Caro, Sarah Lopez, Julia Bateh, Patrick R. Hof, Roger L. Clem, Hirofumi Morishita
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17787-0