Analysis of multiple single nucleotide polymorphisms closely positioned in the ovine <it>PRNP </it>gene using linear fluorescent probes and melting curve analysis

<p>Abstract</p> <p>Background</p> <p>Resistance and susceptibility to scrapie has been associated with single nucleotide polymorphisms located within codons 136, 154 and 171 of the ovine prion protein gene (<it>PRNP</it>). Dual-labelled HyBeacon probes were...

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Bibliographic Details
Main Authors: McDowell David G, Jones Dominic, French David J, Thomson Jim A, Debenham Paul G
Format: Article
Language:English
Published: BMC 2007-08-01
Series:BMC Infectious Diseases
Online Access:http://www.biomedcentral.com/1471-2334/7/90