AKT-independent activation of p38 MAP kinase promotes vascular calcification

Vascular calcification is prevalent in patients with atherosclerosis, and oxidative stress promotes pathogenesis of atherosclerosis. We have previously reported that activation of AKT by oxidative stress induces vascular calcification. Using sodium dichloroacetate (DCA), a previously reported small...

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Bibliographic Details
Main Authors: Youfeng Yang, Yong Sun, Jianye Chen, Wayne E. Bradley, Louis J. Dell’Italia, Hui Wu, Yabing Chen
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717309801