Induction of apoptosis by Fe(salen)Cl through caspase-dependent pathway specifically in tumor cells

Iron-based compounds possess the capability of inducing cell death due to their reactivity with oxidant molecules, but their specificity towards cancer cells and the mechanism of action are hitherto less investigated. A Fe(salen)Cl derivative has been synthesized that remains active in monomer form....

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Bibliographic Details
Main Authors: Nitika Pradhan, B.M. Pratheek, Antara Garai, Ashutosh Kumar, Vikram S Meena, Shyamasree Ghosh, Sujay Singh, Shikha Kumari, T.K. Chandrashekar, Chandan Goswami, Subhasis Chattopadhyay, Sanjib Kar, Prasanta K. Maiti
Format: Article
Language:English
Published: Science Planet Inc. 2017-10-01
Series:Canadian Journal of Biotechnology
Online Access:https://www.canadianjbiotech.com/CAN_J_BIOTECH/Archives/v1/Special Issue/cjb.2017-a135.pdf