Purification of anti-glycoconjugate monoclonal antibodies using newly developed porous zirconia particles
Abstract Here, we describe porous zirconia particles (PZPs) optimized for the purification of immunoglobulins. PZPs, with a pore size of approximately 10 nm, were designed to specifically interact with antibodies via surface modification with a phosphate functional group. A simple PZP purification m...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-02-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-82457-0 |