Role of the DNA Damage Response in Human Papillomavirus RNA Splicing and Polyadenylation

Role of the DNA Damage Response in Human Papillomavirus RNA Splicing and Polyadenylation

Human papillomaviruses (HPVs) have evolved to use the DNA repair machinery to replicate its DNA genome in differentiated cells. HPV activates the DNA damage response (DDR) in infected cells. Cellular DDR factors are recruited to the HPV DNA genome and position the cellular DNA polymerase on the HPV...

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Bibliographic Details
Main Authors: Kersti Nilsson, Chengjun Wu, Stefan Schwartz
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:International Journal of Molecular Sciences
Subjects:
papillomavirus
splicing
polyadenylation
SR proteins
hnRNP C
BRCA1
BCLAF1
TRAP150
DDR
U2AF65
Online Access:http://www.mdpi.com/1422-0067/19/6/1735

Internet

http://www.mdpi.com/1422-0067/19/6/1735

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