Non-programmed transcriptional frameshifting is common and highly RNA polymerase type-dependent

Non-programmed transcriptional frameshifting is common and highly RNA polymerase type-dependent

Abstract Background The viral or host systems for a gene expression assume repeatability of the process and high quality of the protein product. Since level and fidelity of transcription primarily determines the overall efficiency, all factors contributing to their decrease should be identified and...

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Bibliographic Details
Main Authors: Dawid Koscielniak, Ewa Wons, Karolina Wilkowska, Marian Sektas
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Microbial Cell Factories
Subjects:
Recombinant proteins
E. coli RNAP
T7 bacteriophage RNAP
Expression system
GFP reporter
Transcriptional slippage
Online Access:http://link.springer.com/article/10.1186/s12934-018-1034-4

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http://link.springer.com/article/10.1186/s12934-018-1034-4

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