Induction of MiR-21 by Stereotactic Body Radiotherapy Contributes to the Pulmonary Fibrotic Response.

Radiation-induced lung fibrosis, the most serious effect of lung cancer radiotherapy on normal tissue, remains a major technical obstacle to the broader application of radiotherapy to patients with lung cancer. This study describes the use of an image-guided irradiation system in mice mimicking ster...

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Bibliographic Details
Main Authors: Ok-Seon Kwon, Keun-Tae Kim, Eunioo Lee, Myoungjae Kim, Seo-Hyun Choi, Henghong Li, Albert J Fornace, Jae-Ho Cho, Yun-Sil Lee, Ji-Seon Lee, Yoon-Jin Lee, Hyuk-Jin Cha
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4865046?pdf=render