A first-passage approach to diffusion-influenced reversible binding and its insights into nanoscale signaling at the presynapse
Abstract Synaptic transmission between neurons is governed by a cascade of stochastic calcium ion reaction–diffusion events within nerve terminals leading to vesicular release of neurotransmitter. Since experimental measurements of such systems are challenging due to their nanometer and sub-millisec...
Main Authors: | Maria Reva, David A. DiGregorio, Denis S. Grebenkov |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-84340-4 |
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