Roles of Chemokines and Chemokine Receptors in Obesity-Associated Insulin Resistance and Nonalcoholic Fatty Liver Disease

Roles of Chemokines and Chemokine Receptors in Obesity-Associated Insulin Resistance and Nonalcoholic Fatty Liver Disease

Abundant evidence has demonstrated that obesity is a state of low-grade chronic inflammation that triggers the release of lipids, aberrant adipokines, pro-inflammatory cytokines, and several chemokines from adipose tissue. This low-grade inflammation underlies the development of insulin resistance a...

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Bibliographic Details
Main Authors: Liang Xu, Hironori Kitade, Yinhua Ni, Tsuguhito Ota
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Biomolecules
Subjects:
adipose tissue macrophage
chemokines
inflammation
obesity
insulin resistance
nonalcoholic fatty liver disease
macrophage polarization
Kupffer cells
Online Access:http://www.mdpi.com/2218-273X/5/3/1563

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http://www.mdpi.com/2218-273X/5/3/1563

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