Methoxsalen and Bergapten Prevent Diabetes-Induced Osteoporosis by the Suppression of Osteoclastogenic Gene Expression in Mice

Methoxsalen and Bergapten Prevent Diabetes-Induced Osteoporosis by the Suppression of Osteoclastogenic Gene Expression in Mice

This study evaluated whether bergapten and methoxsalen could prevent diabetes-induced osteoporosis and its underlying mechanism. For 10 weeks, bergapten or methoxsalen (0.02%, w/w) was applied to diabetic mice that were provided with a high-fat diet and streptozotocin. Bone mineral density (BMD) and...

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Bibliographic Details
Main Authors: Ju Ri Ham, Ra-Yeong Choi, Hae-In Lee, Mi-Kyung Lee
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:International Journal of Molecular Sciences
Subjects:
diabetes
bone microarchitecture
bergapten
methoxsalen
osteoporosis
Online Access:http://www.mdpi.com/1422-0067/20/6/1298

Internet

http://www.mdpi.com/1422-0067/20/6/1298

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