Inhibition of Lipoxygenases Showed No Benefit for the Musculoskeletal System in Estrogen Deficient Rats

Inhibition of Lipoxygenases Showed No Benefit for the Musculoskeletal System in Estrogen Deficient Rats

BackgroundIn previous studies, we reported the beneficial impact of two lipoxygenase-inhibitors, Baicalein and Zileuton, on osteoporotic bone in a postmenopausal rat model. Whereas subcutaneous Baicalein predominantly improved cortical bone, Zileuton enhanced vertebral and femoral trabecular bone. I...

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Bibliographic Details
Main Authors: Dominik Saul, Friederike Eva Hohl, Max Konrad Franz, Ilka Meyer, Stefan Taudien, Paul Jonathan Roch, Stephan Sehmisch, Marina Komrakova
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Endocrinology
Subjects:
baicalein
bone healing
lipoxygenase-inhibitor
muscle tissue
osteoporosis
zileuton
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.706504/full

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https://www.frontiersin.org/articles/10.3389/fendo.2021.706504/full

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