Sparking Fire Under the Skin? Answers From the Association of Complement Genes With Pemphigus Foliaceus

Sparking Fire Under the Skin? Answers From the Association of Complement Genes With Pemphigus Foliaceus

Skin blisters of pemphigus foliaceus (PF) present concomitant deposition of autoantibodies and components of the complement system (CS), whose gene polymorphisms are associated with susceptibility to different autoimmune diseases. To investigate these in PF, we evaluated 992 single-nucleotide polymo...

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Bibliographic Details
Main Authors: Valéria Bumiller-Bini, Gabriel Adelman Cipolla, Rodrigo Coutinho de Almeida, Maria Luiza Petzl-Erler, Danillo Gardenal Augusto, Angelica Beate Winter Boldt
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
pemphigus foliaceus
complement
lectin pathway
acantholysis
membrane attack complex
alternative pathway
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00695/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00695/full

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