The epithelial sodium channel (ENaC) establishes a trafficking vesicle pool responsible for its regulation.

The epithelial sodium channel (ENaC) establishes a trafficking vesicle pool responsible for its regulation.

The epithelial sodium channel (ENaC) is the rate-limiting step for sodium reabsorption across tight epithelia. Cyclic-AMP (cAMP) stimulation promotes ENaC trafficking to the apical surface to increase channel number and transcellular Na(+) transport. Removal of corticosteroid supplementation in a cu...

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Bibliographic Details
Main Authors: Robert S Edinger, Carol A Bertrand, Christine Rondandino, Gerard A Apodaca, John P Johnson, Michael B Butterworth
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3460899?pdf=render

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http://europepmc.org/articles/PMC3460899?pdf=render

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