A vicious circle between insulin resistance and inflammation in nonalcoholic fatty liver disease

Abstract Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum of diseases, including simple steatosis, nonalcoholic steatohepatitis (NASH), liver cirrhosis and hepatocellular carcinoma. Lipotoxicity, insulin resistance (IR) and inflammation are involved in the disease process. Lipotoxicity...

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Bibliographic Details
Main Authors: Zhonge Chen, Rong Yu, Ying Xiong, Fangteng Du, Shuishan Zhu
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Lipids in Health and Disease
Online Access:http://link.springer.com/article/10.1186/s12944-017-0572-9