IL-6 Reduces Mitochondrial Replication, and IL-6 Receptors Reduce Chronic Inflammation in NAFLD and Type 2 Diabetes

IL-6 Reduces Mitochondrial Replication, and IL-6 Receptors Reduce Chronic Inflammation in NAFLD and Type 2 Diabetes

Interleukin (IL)-6 family cytokines act through a receptor complex with gp130 subunits. IL-6 is a pleiotropic cytokine that regulates inflammation and liver regeneration. Mitochondria are the first to respond to stress and adapt their dynamics in conditions of damage. In this regard, the study aimed...

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Bibliographic Details
Main Authors: Daria Skuratovskaia, Aleksandra Komar, Maria Vulf, Hung Vu Quang, Egor Shunkin, Larisa Volkova, Natalia Gazatova, Pavel Zatolokin, Larisa Litvinova
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
IL-6
IL-11
gp130/sIL-6Rb
sIL-6Ra
obesity
NAFLD
Online Access:https://www.mdpi.com/1422-0067/22/4/1774

Internet

https://www.mdpi.com/1422-0067/22/4/1774

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