Adaption of seasonal H1N1 influenza virus in mice.

The experimental infection of a mouse lung with influenza A virus has proven to be an invaluable model for studying the mechanisms of viral adaptation and virulence. The mouse adaption of human influenza A virus can result in mutations in the HA and other proteins, which is associated with increased...

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Bibliographic Details
Main Authors: Lili Xu, Linlin Bao, Fengdi Li, Qi Lv, Yila Ma, Jiangfang Zhou, Yanfeng Xu, Wei Deng, Lingjun Zhan, Hua Zhu, Chunmei Ma, Yuelong Shu, Chuan Qin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3241702?pdf=render