Knockout of Pannexin-1 Induces Hearing Loss

Knockout of Pannexin-1 Induces Hearing Loss

Mutations of gap junction connexin genes induce a high incidence of nonsyndromic hearing loss. Pannexin genes also encode gap junctional proteins in vertebrates. Recent studies demonstrated that Pannexin-1 (Panx1) deficiency in mice and mutation in humans are also associated with hearing loss. So fa...

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Bibliographic Details
Main Authors: Jin Chen, Chun Liang, Liang Zong, Yan Zhu, Hong-Bo Zhao
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:International Journal of Molecular Sciences
Subjects:
Panx1
deafness
hearing
gap junction
inner ear
ABR
DPOAE
CM
Online Access:http://www.mdpi.com/1422-0067/19/5/1332

Internet

http://www.mdpi.com/1422-0067/19/5/1332

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