Cross-reactive T cells are involved in rapid clearance of 2009 pandemic H1N1 influenza virus in nonhuman primates.

In mouse models of influenza, T cells can confer broad protection against multiple viral subtypes when antibodies raised against a single subtype fail to do so. However, the role of T cells in protecting humans against influenza remains unclear. Here we employ a translational nonhuman primate model...

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Bibliographic Details
Main Authors: Jason T Weinfurter, Kevin Brunner, Saverio V Capuano, Chengjun Li, Karl W Broman, Yoshihiro Kawaoka, Thomas C Friedrich
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3213121?pdf=render