Mapping the topographic epitope landscape on the urokinase plasminogen activator receptor (uPAR) by surface plasmon resonance and X-ray crystallography

Mapping the topographic epitope landscape on the urokinase plasminogen activator receptor (uPAR) by surface plasmon resonance and X-ray crystallography

The urokinase-type plasminogen activator receptor (uPAR or CD87) is a glycolipid-anchored membrane protein often expressed in the microenvironment of invasive solid cancers and high levels are generally associated with poor patient prognosis (Kriegbaum et al., 2011 [1]). uPAR is organized as a dynam...

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Bibliographic Details
Main Authors: Baoyu Zhao, Sonu Gandhi, Cai Yuan, Zhipu Luo, Rui Li, Henrik Gårdsvoll, Valentina de Lorenzi, Nicolai Sidenius, Mingdong Huang, Michael Ploug
Format: Article
Language:English
Published: Elsevier 2015-12-01
Series:Data in Brief
Subjects:
uPAR
CD87
Epitope mapped antibodies
SPR
Allostery
Hot spots
Vitronectin
Cancer invasion
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340915001833

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http://www.sciencedirect.com/science/article/pii/S2352340915001833

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