Soluble Guanylyl Cyclase is Reduced in Airway Smooth Muscle Cells From a Murine Model of Allergic Asthma

Airway remodeling plays an important role in the development of airway hyperresponsiveness in asthma. Muscarinic agonists such as carbamylcholine increased cyclic GMP (cGMP) levels in bovine tracheal smooth muscle strips, via stimulation of NO-sensitive soluble guanylylcyclase (NO-sGC), which is an...

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Bibliographic Details
Main Authors: Fabiola Placeres-Uray, PhD, Ramona González de Alfonzo, PhD, Itala Lippo de Becemberg, MD, PhD, Marcelo J. Alfonzo, MD, PhD
Format: Article
Language:English
Published: Elsevier 2010-01-01
Series:World Allergy Organization Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1939455119304910