Asynchrony between virus diversity and antibody selection limits influenza virus evolution
Seasonal influenza viruses create a persistent global disease burden by evolving to escape immunity induced by prior infections and vaccinations. New antigenic variants have a substantial selective advantage at the population level, but these variants are rarely selected within-host, even in previou...
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-11-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/62105 |