Intracellular and Tissue Levels of Vitamin B12 in Hepatocytes Are Modulated by CD320 Receptor and TCN2 Transporter

Intracellular and Tissue Levels of Vitamin B12 in Hepatocytes Are Modulated by CD320 Receptor and TCN2 Transporter

The liver mass constitutes hepatocytes expressing receptors for vitamin B12 (B12)-bound transporters in circulation. However, intrahepatic and circulating B12 interrelationship levels remain unclear. We assessed the intracellular B12 levels at various circulating B12 concentrations in human HepG2 ce...

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Bibliographic Details
Main Authors: Joseph Boachie, Antonysunil Adaikalakoteswari, Ilona Goljan, Jinous Samavat, Felino R. Cagampang, Ponnusamy Saravanan
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
vitamin B12 (cobalamin), transcobalamin
hepatocytes
intrinsic factor
B12 receptor (CD320), B12 transporter (transcobalamin II
TCN2)
Online Access:https://www.mdpi.com/1422-0067/22/6/3089

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https://www.mdpi.com/1422-0067/22/6/3089

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