Astaxanthin Suppresses MPP+-Induced Oxidative Damage in PC12 Cells through a Sp1/NR1 Signaling Pathway

Objective: To investigate astaxanthin (ATX) neuroprotection, and its mechanism, on a 1-methyl-4-phenyl-pyridine ion (MPP+)-induced cell model of Parkinson’s disease. Methods: Mature, differentiated PC12 cells treated with MPP+ were used as an in vitro cell model. The MTT assay was used to investigat...

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Bibliographic Details
Main Authors: Xiaochun Chen, Yuangui Zhu, Bixia Huang, Xiaodong Zhang, Qinyong Ye
Format: Article
Language:English
Published: MDPI AG 2013-03-01
Series:Marine Drugs
Subjects:
Sp1
NR1
Online Access:http://www.mdpi.com/1660-3397/11/4/1019