The β amyloid peptide can act as a modular aggregation domain

The β amyloid peptide can act as a modular aggregation domain

Although there is compelling evidence that the β amyloid peptide (Aβ) can be centrally involved in Alzheimer's disease, the natural role (if any) of this peptide remains unclear. Here we use green fluorescent protein (GFP) fusions to demonstrate that the Aβ sequence, like prion domains, can act...

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Bibliographic Details
Main Authors: Christopher D. Link, Virginia Fonte, Christine M. Roberts, Brian Hiester, Michael A. Silverman, Gretchen H. Stein
Format: Article
Language:English
Published: Elsevier 2008-12-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
C. elegans
Transgenic
Neurodegeneration
γ-secretase
α-secretase
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108001897

Internet

http://www.sciencedirect.com/science/article/pii/S0969996108001897

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