Study of the Tissue Distribution of TLQP-21 in Mice Using [18F]JMV5763, a Radiolabeled Analog Prepared via [18F]Aluminum Fluoride Chelation Chemistry

Study of the Tissue Distribution of TLQP-21 in Mice Using [18F]JMV5763, a Radiolabeled Analog Prepared via [18F]Aluminum Fluoride Chelation Chemistry

TLQP-21 is a neuropeptide that is involved in the control of several physiological functions, including energy homeostasis. Since TLQP-21 could oppose the early phase of diet-induced obesity, it has raised a huge interest, but very little is known about its mechanisms of action on peripheral tissues...

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Bibliographic Details
Main Authors: Elia A. Turolla, Silvia Valtorta, Elena Bresciani, Jean-Alain Fehrentz, Liliana Giuliano, Stefano Stucchi, Sara Belloli, Paolo Rainone, Francesco Sudati, Laura Rizzi, Laura Molteni, Pascal Verdiè, Jean Martinez, Antonio Torsello, Rosa Maria Moresco, Sergio Todde
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Pharmacology
Subjects:
TLQP-21
VGF
obesity
fluorine-18
radiolabeling
PET
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01274/full

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https://www.frontiersin.org/article/10.3389/fphar.2018.01274/full

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