KSHV Latency Locus Cooperates with Myc to Drive Lymphoma in Mice.

Kaposi sarcoma-associated herpesvirus (KSHV) has been linked to Kaposi sarcoma and B-cell malignancies. Mechanisms of KSHV-induced oncogenesis remain elusive, however, in part due to lack of reliable in vivo models. Recently, we showed that transgenic mice expressing the KSHV latent genes, including...

Full description

Bibliographic Details
Main Authors: Sang-Hoon Sin, Yongbaek Kim, Anthony Eason, Dirk P Dittmer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005135