Effects of silencing the HIF-1α gene on the expression of BSP and osterix in rat BMMSCs under tension

Objective To explore the effect of hypoxia inducible factor 1α (HIF⁃1α) gene silencing in rat bone mar⁃ row mesenchymal stem cells (BMMSCs) under mechanical distraction on the expression of bone sialoprotein (BSP) and osterix and to provide a new idea for repairing bone defects with BMMSCs. Method...

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Bibliographic Details
Main Authors: LIU Ying, YANG Jing, LI Yazhen, YAN Xiao, ZHANG Qiang, REN Dapeng, YANG Fang, YUAN Xiao, GUO Qingyuan
Format: Article
Language:zho
Published: Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2019-05-01
Series:口腔疾病防治
Online Access:http://www.kqjbfz.com/EN/10.12016/j.issn.2096-1456.2019.05.003