Divergence in alternative polyadenylation contributes to gene regulatory differences between humans and chimpanzees

While comparative functional genomic studies have shown that inter-species differences in gene expression can be explained by corresponding inter-species differences in genetic and epigenetic regulatory mechanisms, co-transcriptional mechanisms, such as alternative polyadenylation (APA), have receiv...

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Bibliographic Details
Main Authors: Briana E Mittleman, Sebastian Pott, Shane Warland, Kenneth Barr, Claudia Cuevas, Yoav Gilad
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/62548