Effects of hypoxia and nanocarrier size on pH-responsive nano-delivery system to solid tumors

Abstract One of the special features of solid tumors is the acidity of the tumor microenvironment, which is mainly due to the presence of hypoxic regions. Therefore, pH-responsive drug delivery systems have recently been highly welcomed. In the present study, a comprehensive mathematical model is pr...

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Bibliographic Details
Main Authors: M. Soltani, Mohammad Souri, Farshad Moradi Kashkooli
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98638-w