Genomics and High-Resolution Typing Confirm Predominant Clonal Evolution Down to a Microevolutionary Scale in <i>Trypanosoma cruzi</i>

Genomics and High-Resolution Typing Confirm Predominant Clonal Evolution Down to a Microevolutionary Scale in <i>Trypanosoma cruzi</i>

<i>Trypanosoma cruzi</i>, the agent of Chagas disease, is a paradigmatic case of the predominant clonal evolution (PCE) model, which states that the impact of genetic recombination in pathogens’ natural populations is not sufficient to suppress a persistent phylogenetic signal at all evo...

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Bibliographic Details
Main Authors: Michel Tibayrenc, Francisco J. Ayala
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Pathogens
Subjects:
Chagas disease
parasitic protozoa
clonality threshold
genetic recombination
phylogenetic signal
Russian doll pattern
Online Access:https://www.mdpi.com/2076-0817/9/5/356

Internet

https://www.mdpi.com/2076-0817/9/5/356

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