Development, Characterization, and Evaluation of SLN-Loaded Thermoresponsive Hydrogel System of Topotecan as Biological Macromolecule for Colorectal Delivery

Development, Characterization, and Evaluation of SLN-Loaded Thermoresponsive Hydrogel System of Topotecan as Biological Macromolecule for Colorectal Delivery

Background. Chemotherapeutic drugs cause severe toxicities if administered unprotected, without proper targeting, and controlled release. In this study, we developed topotecan- (TPT-) loaded solid lipid nanoparticles (SLNs) for their chemotherapeutic effect against colorectal cancer. The TPT-SLNs we...

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Bibliographic Details
Main Authors: R. Xing, O. Mustapha, T. Ali, M. Rehman, S. S. Zaidi, A. Baseer, S. Batool, M. Mukhtiar, S. Shafique, M. Malik, S. Sohail, Z. Ali, F. Zahid, A. Zeb, F. Shah, A. Yousaf, F. Din
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2021/9968602

Internet

http://dx.doi.org/10.1155/2021/9968602

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