RASAL1 induces to downregulate the SCD1, leading to suppression of cell proliferation in colon cancer via LXRα/SREBP1c pathway

Abstract Background Recent studies have confirmed that RASAL1 has an antitumor effect in many cancers, but its functional role and the molecular mechanism underlying in colon cancer has not been investigated. Results We collected human colon cancer tissues and adjacent non-tumor tissues, human colon...

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Bibliographic Details
Main Authors: Guangchuan Wang, Zhen Li, Xiao Li, Chunqing Zhang, Lipan Peng
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Biological Research
Subjects:
Online Access:https://doi.org/10.1186/s40659-019-0268-x