Pretreatment with apoaequorin protects hippocampal CA1 neurons from oxygen-glucose deprivation.

Ischemic stroke affects ∼795,000 people each year in the U.S., which results in an estimated annual cost of $73.7 billion. Calcium is pivotal in a variety of neuronal signaling cascades, however, during ischemia, excess calcium influx can trigger excitotoxic cell death. Calcium binding proteins help...

Full description

Bibliographic Details
Main Authors: Julia A Detert, Erin L Adams, Jacob D Lescher, Jeri-Anne Lyons, James R Moyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24244400/?tool=EBI